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Age-related differences in sensitivity to the antinociceptive effects of kappa opioids in adult male rats

✍ Scribed by Mark A. Smith; Adam M. French


Publisher
Springer
Year
2002
Tongue
English
Weight
120 KB
Volume
162
Category
Article
ISSN
0033-3158

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Age-related differences in susceptibilit
✍ Parvaneh Espandiari; Jun Zhang; Laura K. Schnackenberg; Terry J. Miller; Alan Kn πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 371 KB

## Abstract A multi‐age rat model was evaluated as a means to identify a potential age‐related difference in liver injury following exposure to valproic acid (VPA), a known pediatric hepatotoxic agent. Different age groups of Sprague‐Dawley (SD) rats (10‐, 25‐, 40‐, 80‐day‐old) were administered VP