We have investigated the links between electrical excitation and contraction in mammalian heart muscle. Using isolated single cells from adult rat ventricle, a whole-cell voltage-clamp technique and quantitative fluorescence microscopy, we have measured simultaneously calcium current (ICa) and [Ca2+
β¦ LIBER β¦
Age-related differences in excitation-contraction coupling in rat papillary muscle
β Scribed by J. M. Capasso; R. M. Remily; E. H. Sonnenblick
- Publisher
- Springer
- Year
- 1983
- Tongue
- English
- Weight
- 869 KB
- Volume
- 78
- Category
- Article
- ISSN
- 0300-8428
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## Abstract The objective of the present investigation was to determine the effects of muscle unloadingβa form of subtotal disuseβ on the morphology of the neuromuscular junction (NMJ) in younger and aged animals. Sixteen aged (22 months) and 16 young adult (8 months) male Fischer 344 rats were ass