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Age-related changes of neuron numbers in the frontal cortex of a transgenic mouse model of Alzheimer’s disease

✍ Scribed by Marijke A. M. Lemmens; Annerieke S. R. Sierksma; Bart P. F. Rutten; Frank Dennissen; Harry W. M. Steinbusch; Paul J. Lucassen; Christoph Schmitz

Publisher
Springer
Year
2011
Tongue
English
Weight
514 KB
Volume
216
Category
Article
ISSN
0340-2061

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## Abstract The cerebral deposition of amyloid β‐peptide, a central event in Alzheimer's disease (AD) pathogenesis, begins several years before the onset of clinical symptoms. Noninvasive detection of AD pathology at this initial stage would facilitate intervention and enhance treatment success. In