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Age-related changes in unscheduled DNA synthesis by rat hepatocytes

✍ Scribed by Marguerite M. Plesko; Arlan Richardson


Book ID
115758041
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
362 KB
Volume
118
Category
Article
ISSN
0006-291X

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✍ Akihito Ishigami; George S. Roth πŸ“‚ Article πŸ“… 1994 πŸ› John Wiley and Sons 🌐 English βš– 645 KB

We examined epinephrine-and isoproterenol-stimulated DNA synthesis in primary cultured hepatocytes from 6-, 12-, and 24-month-old rats. Epinephrinestimulated DNA synthesis in 6-month-old rat hepatocytes began after 20 h and reachcd a maximum at 50 h. Similarly, isoproterenol-stimulated DNA synthesis