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Age-related changes in the occurrence and characteristics of thymic CD4+ CD25+ T cells in mice

✍ Scribed by Ewa Kozlowska; Marzena Biernacka; Marzena Ciechomska; Nadzieja Drela


Book ID
108782162
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
384 KB
Volume
122
Category
Article
ISSN
0019-2805

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## Abstract Advancing age is associated with significant alterations in immune functions, including a decline in CD4 T cell function, in both mice and humans. In our previous report, we showed that CD4^+^CD25^–^ T cells in aged (24‐month‐old) mice, especially after __in vitro__ pre‐stimulation of t