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Age-related changes in the mRNA levels of CYP1A1, CYP2B1/2 and CYP3A1 isoforms in rat small intestine

✍ Scribed by Artur Pałasz; Anna Wiaderkiewicz; Ryszard Wiaderkiewicz; Piotr Czekaj; Beata Czajkowska; Tomasz Lebda-Wyborny; Aneta Piwowarczyk; Aleksandra Bryzek


Book ID
113100679
Publisher
Springer-Verlag
Year
2011
Tongue
English
Weight
335 KB
Volume
7
Category
Article
ISSN
1555-8932

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Ontogeny of hepatic CYP1A2 and CYP2E1 ex
✍ Fawzy A. Elbarbry; Patrick J. McNamara; Jane Alcorn 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 404 KB 👁 1 views

## Abstract We report a comprehensive examination of rat hepatic CYP1A2 and CYP2E1 ontogeny. We compare the data to human data to determine the rat's capacity as a model to identify CYP‐mediated mechanisms underlying age‐dependent differences in susceptibility to toxicity. We evaluated CYP expressi