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Age-related Changes in Neurotrophic Factors Expression in Skeletal Muscle Undergoing Atrophy

โœ Scribed by Yun Shi; Yuhong Liu; Yan Li; Ryan T. Hamilton; Amanda L. Jernigan; Youngmok C. Jang; Holly Van Remmen


Book ID
113632513
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
72 KB
Volume
51
Category
Article
ISSN
0891-5849

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Glial cell line-derived neurotrophic factor (GDNF) has been shown to exert neurotrophic effects on motor neurons as well as mesencephalic dopaminergic neurons. Because GDNF promotes survival of motor neurons in vivo and in vitro and rescues motor neurons from naturally occurring cell death, the pote