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Age increase in the threshold of sensitivity of the tonic region of the hypothalamic sex center to inhibition by estradiol in female rats

✍ Scribed by V. N. Anisimov; V. E. Mokshin; V. M. Dil'man

Publisher
Springer US
Year
1978
Tongue
English
Weight
279 KB
Volume
86
Category
Article
ISSN
0007-4888

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The administration of the GABA-blocking agents picrotoxin and bicuculline to adult (2.5-3 months old) CBA/HZgr mice resulted in the appearance of convulsions, the occurrence and/or lethality of which was greater in males than in females. The latency of picrotoxin-induced convulsions was also shorter