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Age-dependent regulation of mammalian DNA synthesis and cell proliferation In vivo

โœ Scribed by Richard C. Adelman; Gary Stein; George S. Roth; David Englander

Book ID
119024683
Publisher
Elsevier Science
Year
1972
Tongue
English
Weight
499 KB
Volume
1
Category
Article
ISSN
0047-6374

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It is well known that cell proliferation (and hence, DNA synthesis) declines in human diploid fibroblast-like cells with increasing passage number. It is not clear whether DNA synthesis declines in the remaining cells that are still actively proliferating. Estimations of cell kinetic parameters perm