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Age-dependent reduction in sialidase activity of nuclear membranes from mouse brain

โœ Scribed by Megumi Saito; Hitoshi Hagita; Masaki Ito; Susumu Ando; Robert K. Yu

Book ID
114253730
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
187 KB
Volume
37
Category
Article
ISSN
0531-5565

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Characterization of sialidase activity i
Characterization of sialidase activity in mouse synaptic plasma membranes and its age-related changes
โœ Dr. M. Saito; Y. Tanaka; C.-P. Tang; R. K. Yu; S. Ando ๐Ÿ“‚ Article ๐Ÿ“… 1995 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 585 KB

Sialidase activity in synaptic plasma membranes (SPM) isolated from C57BL/6 mouse brain was examined using exogenous ganglioside substrates. The enzyme activity directed toward GM3 showed sharp pH dependency with optimal pH of 4.0, and was greatly enhanced by Triton CF-54, Nonidet P-40 or CHAPS. The