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Age-dependent effects of lead on [3H]MK-801 binding to the NMDA receptor-gated ionophore: in vitro and in vivo studies

✍ Scribed by Guilarte, Tomás R.; Miceli, Renée C.

Book ID
122343299
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
401 KB
Volume
148
Category
Article
ISSN
0304-3940

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Effects of age and visual experience on
Effects of age and visual experience on [3H] MK801 binding to NMDA receptors in the kitten visual cortex
✍ I. J. Reynolds; M. F. Bear 📂 Article 📅 1991 🏛 Springer-Verlag 🌐 English ⚖ 520 KB

We have investigated the postnatal development of N-methyl-D-aspartate (NMDA) receptors in kitten neocortex by measuring the density of [3H] MK801 binding sites. NMDA receptor density in area 17 markedly increases between postnatal day 7 and 35, and then remains at a high level into adulthood. Simil