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Age-dependent changes in noradrenergic locus coeruleus system in wild-type and APP23 transgenic mice

✍ Scribed by Patricia Szot; Debby Van Dam; Sylvia S. White; Allyn Franklin; Matthias Staufenbiel; Peter Paul De Deyn

Book ID: 116771605
Publisher: Elsevier Science
Year: 2009
Tongue: English
Weight: 312 KB
Volume: 463
Category: Article
ISSN: 0304-3940
DOI: 10.1016/j.neulet.2009.07.055

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## Abstract Neurotrophins, including brain‐derived neurotrophic factor (BDNF), nerve growth factor (NGF), and neurotrophin‐3 (NT‐3), have repeatedly been shown to be involved in the pathophysiology of Alzheimer's disease (AD). Recent studies have claimed that these neurotrophic factors are importan