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Age-dependent change of metabolic capacity and genotoxic injury in rat intestine

✍ Scribed by H.R.H. Patel; A. Hewer; J.D. Hayes; D.H. Phillips; F.C. Campbell

Book ID
114009595
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
197 KB
Volume
113
Category
Article
ISSN
0009-2797

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## Abstract The contribution of gastrointestinal tract (GIT), liver, and lung towards the first‐pass metabolism of acetaminophen was examined using 3‐week‐old, 10‐week‐old and 1‐year‐old rats after administration of 30mgkg^βˆ’1^ doses by intra‐arterial, intravenous, intraperitoneal, and oral routes.