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Age-dependent accumulation of monoclonal CD4+CD8+double positive T lymphocytes in the peripheral blood of the elderly

โœ Scribed by Paolo Ghia; Giuseppina Prato; Stefania Stella; Cristina Scielzo; Massimo Geuna; Federico Caligaris-Cappio


Book ID
108675489
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
300 KB
Volume
139
Category
Article
ISSN
0007-1048

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The antigenic specificity of the majority of T lymphocytes in the peripheral blood is determined by the combination of a and p variable region chains present in the T cell receptor complex. Currently, the Vp chains are grouped into 25 families. Historically, determination of Vp usage has relied on d