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Age-dependence in capacity-limited uptake kinetics of propranolol by isolated rat hepatocytes

✍ Scribed by Iwamoto Kikuo; Watanabe Jun; Satoh Mariko

Book ID
115778839
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
639 KB
Volume
35
Category
Article
ISSN
0006-2952

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πŸ“œ SIMILAR VOLUMES

Comparison of uptake kinetics in freshly
Comparison of uptake kinetics in freshly isolated suspensions and short-term primary cultures of rat hepatocytes
✍ Veerapol Kukongviriyapan; Neill H. Stacey πŸ“‚ Article πŸ“… 1989 πŸ› John Wiley and Sons 🌐 English βš– 784 KB

The apparent kinetics of uptake of various model substrates were examined for hepatocytes in suspension and primary culture up to 72 h. The ability of hepatocytes to take up taurocholate and ouabain was decreased in culture. Vmax for uptake of both substrates diminished rapidly with increasing time