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Age dependence and charge isomers of bovine erythrocyte Cu2Zn2superoxide dismutase

✍ Scribed by Alfred Gärtner; Monika Schroth-Pollmann; Ulrich Weser

Book ID
108324233
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
1013 KB
Volume
107
Category
Article
ISSN
0020-1693

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✍ L. Banci; I. Bertini; P. Turano 📂 Article 📅 1991 🏛 Springer 🌐 English ⚖ 554 KB

The activity profile of the Cu2Zn2HSOD Ile-137 mutant has a pKa of 9.6, i.e. one unit lower than the wild type (WT). This property has allowed us to investigate the inactive high pH form of the enzyme before denaturation occurs. The electronic and EPR spectra do not change with the above pKa. The 1H