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Age-at-onset in restless legs syndrome: A clinical and polysomnographic study

✍ Scribed by S. Whittom; Y. Dauvilliers; M.-H. Pennestri; F. Vercauteren; N. Molinari; D. Petit; J. Montplaisir


Book ID
116884325
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
178 KB
Volume
9
Category
Article
ISSN
1389-9457

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Restless legs syndrome in Friedreich ata
✍ Birgit Frauscher; Sascha Hering; Birgit HΓΆgl; Viola Gschliesser; Hanno Ulmer; We πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 118 KB

Friedreich ataxia (FA) is the most common type of hereditary ataxia. Frataxin deficiency due to a GAA expansion in the first intron of chromosome 9 results in intramitochondrial iron accumulation. On the basis of the patients' complaints about sleep disturbance and pathophysiological considerations,