## Abstract Infection with the gastric bacterium __Helicobacter pylori__ (in particular infection with CagAβpositive strains) and smoking have been identified as risk factors for the development of gastric cancer. Both risk factors are typically acquired early in life and prevail over decades if no
Age at Acquisition of Helicobacter pylori Infection: Comparison of Two Areas with Contrasting Risk of Gastric Cancer
β Scribed by M. Constanza Camargo; M. Clara Yepez; Cristina Ceron; Nancy Guerrero; Luis E. Bravo; Pelayo Correa; Elizabeth T.H. Fontham
- Book ID
- 111667974
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- English
- Weight
- 161 KB
- Volume
- 9
- Category
- Article
- ISSN
- 1083-4389
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We conducted a longitudinal cohort study to determine the association of Helicobacter pylori infection and the progression of chronic atrophic gastritis (CAG) with gastric cancer. A cohort of 4655 healthy asymptomatic subjects was followed for a mean period of 7.7 years. H. pylori infection was esta
Overexpression of cyclooxygenase (COX)-2 has been implicated in the development of cancer. This study aimed to evaluate the relationship between genetic variants in COX-2 promoter interacting with Helicobacter pylori and the susceptibility to gastric cancer (GC). Three COX-2 polymorphisms -1290A>G (