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Age-associated skewing of X-inactivation ratios of blood cells in normal females: a candidate-gene analysis approach

✍ Scribed by Pierre Chagnon; Sylvie Provost; Claude Belisle; Véronique Bolduc; Marianne Gingras; Lambert Busque


Book ID
113616003
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
163 KB
Volume
33
Category
Article
ISSN
0301-472X

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We report on a thrombocytopenic female belonging to a pedigree with the Wiskott-Aldrich syndrome (WAS). Restriction fragment length polymorphism (RFLP) analysis with probe M27 beta, closely linked to the WAS gene, demonstrated that she is a carrier of WAS. Both small-sized and normal-sized platelets