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Age-associated modifications of Base Excision Repair activities in human skin fibroblast extracts

✍ Scribed by Bénédicte Pons; Anne-Sophie Belmont; Gwénaëlle Masson-Genteuil; Violaine Chapuis; Thierry Oddos; Sylvie Sauvaigo

Book ID
113776319
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
286 KB
Volume
131
Category
Article
ISSN
0047-6374

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The responses of normal human skin fibroblasts exposed to simulated sunlight produced by a solar simulator were examined. The parameters investigated were cellular survival, excision repair and the inhibition and recovery of DNA synthesis. The latter two effects were examined using the bromodeoxyuri