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Age-associated micronuclei containing centromeres and the sex chromosomes in lymphocytes of men

✍ Scribed by J. Catalan; K. Autio; M. Sorsa; H. Norppa

Book ID
114133352
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
179 KB
Volume
360
Category
Article
ISSN
0165-1161

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In PHA-cultured lymphocytes, about 8% of metaphases from 32 women were aneuploid compared to 4% of metaphases from 35 men. A significant part of this aneuploidy was characterized by sex chromosome involvement: in women, the loss of gain of X chromosomes; in men, the gain of X chromosomes and the los