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Age and Visual Experience-dependent Expression of NMDAR1 Splice Variants in Rat Retina

✍ Scribed by Georgia Manta; Athanasios D. Spathis; Stavros Taraviras; Elias D. Kouvelas; Adamantia Mitsacos

Book ID: 106484765
Publisher: Springer
Year: 2011
Tongue: English
Weight: 318 KB
Volume: 36
Category: Article
ISSN: 0364-3190
DOI: 10.1007/s11064-011-0467-5

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## Abstract Glutamate is the major excitatory neurotransmitter in the vertebrate retina. The N‐methyl‐D‐aspartate glutamate receptor (NMDAR) is assembled as a tetramer containing NR1 and NR2, and possibly NR3 subunits, NR1 being essential for the formation of the ion channel. The NMDAR1 (NR1) gene