## Abstract The rat epigastric island flap model is commonly used to explore ischemiaβrelated phenomena. We sought to evaluate strain differences in tolerance to ischemia using two commonly used rat strains: SpragueβDawley and Lewis. Epigastric flaps (3 Γ 6 cm) based on the superficial epigastric a
Age and tolerance to secondary ischemia in rat epigastric flaps
β Scribed by Michael F. Angel; Andrew M. Ress; L. R. Amiss; Raymond F. Morgan
- Book ID
- 102510635
- Publisher
- John Wiley and Sons
- Year
- 1994
- Tongue
- English
- Weight
- 271 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0738-1085
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β¦ Synopsis
Abstract
The use of microvascular procedures is increasing as the population continues to age. The purpose of this study was to observe the survival of skin flaps after ischemic injury. Skin flaps (n = 50) underwent either 3 hours of primary (1Β°) or secondary (2Β°) venous occlusion in young (2β3 mo) and old (18β22 mo) rats. Skin flap survival was assessed on postoperative day 7. Survival rates for young and old after 3 hours of 1Β° ischemia was 100% and 90% (ns). Survival rats for young and old after 2Β° ischemia were 67% and 47% (ns). Β© 1994 WileyβLiss, Inc.
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## Abstract Extended groin flaps in rats were used to explore the relationship of time and temperature of ischemic storage to the ultimate survival of free flaps. The maximum period of ischemia with 100% survival was found to be six hours for storage at a normothermic range (20β 25β C) and 48 hours