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Age and sex influence expression of plasmid DNA directly injected into mouse skeletal muscle

โœ Scribed by Dominic J. Wells; Geoffrey Goldspink


Book ID
115926677
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
337 KB
Volume
306
Category
Article
ISSN
0014-5793

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Previous studies have suggested that direct injection of naked plasmid DNA (pDNA) into solid tumors can be a useful method for in vivo gene transfer into tumor cells. To gain more insight into this approach, we studied the disposition and gene expression characteristics of naked pDNA after intratumo