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AFM study of the interaction of cytochrome P450 2C9 with phospholipid bilayers

✍ Scribed by Matthew R. Nussio; Nicolas H. Voelcker; John O. Miners; Benjamin C. Lewis; Matthew J. Sykes; Joseph G. Shapter


Book ID
108091505
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
760 KB
Volume
163
Category
Article
ISSN
0009-3084

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In vitro incubation of rat liver microsomes with ['4C]-furan in the presence of NADPH resulted in the covalent incorporation of furan-derived radioactivity in microsomal protein. Compared to microsomes from untreated rats a two-to threefold increase in binding was observed with microsomes from pheno