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Aflatoxin B1-specific cytochrome P-450 isozyme (P-450-AFB) inducible by 3-methylcholanthrene in golden hamsters

โœ Scribed by Fukuhara Morio; Mizokami Keinosuke; Sakaguchi Masahiro; Niimura Yasuko; Kato Kazue; Inouye Sakae; Takanaka Akira


Book ID
115781353
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
865 KB
Volume
39
Category
Article
ISSN
0006-2952

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Aflatoxin B1 metabolism by 3-methylchola
โœ Lai, T. S. ;Chiang, J. Y. L. ๐Ÿ“‚ Article ๐Ÿ“… 1990 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 688 KB

We have studied the activation of aflatoxin B, by hamster liver microsomes and purified hamster cytochrome P-450 isozymes using a umu mutagen test. The hamster liver microsomes or S-9 fractions were much more active than rat liver microsomes or s-9 fractions in the activation of umu gene expression