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Affinity labeling of ribonucleotide reductase by the 2′,3′-dialdehyde derivatives of ribonucleotides

✍ Scribed by Pei Kuo Tsai; Harry P.C. Hogenkamp

Book ID
115705699
Publisher
Elsevier Science
Year
1983
Tongue
English
Weight
809 KB
Volume
226
Category
Article
ISSN
0003-9861

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## Abstract This article focuses on the first step of the catalytic mechanism for the reduction of ribonucleotides catalyzed by the enzyme Ribonucleotide Reductase (RNR). This corresponds to the activation of the substrate. In this work a large model of the active site region involving 130 atoms wa