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Affinity for the dopamine D2 receptor predicts neuroleptic potency in decreasing the speed of an internal clock

✍ Scribed by Warren H. Meck

Book ID
113220534
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
514 KB
Volume
25
Category
Article
ISSN
0091-3057

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## Abstract In this study we examined the selectivity of dopamine (DA) for rat striatal DA D~1~ and D~2~ receptors. In a Krebs‐HEPES buffer, the K~i~ values of DA for D~1~ binding sites (labelled with [^3^H]SCH23390) and D~2~ binding sites (labelled with [^3^H]spiroperidol) in striatal membranes am