𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Affinity enhancement of bispecific antibody against two different epitopes in the same antigen

✍ Scribed by Hong Seok Cheong; Jin Soo Chang; Jong Myun Park; Si Myung Byun


Book ID
117055129
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
515 KB
Volume
173
Category
Article
ISSN
0006-291X

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Tumor targeting with newly designed bipa
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In an attempt to improve tumor targeting and tumor retention time of monoclonal antibodies (MAbs), we prepared biparatopic antibodies (BpAbs) having the capability of binding 2 different non-overlapping epitopes on the same target antigen molecule, namely, the carcinoembryonic antigen (CEA). Six BpA