𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Affinities of some common opioid analgesics towards four binding sites in mouse brain

✍ Scribed by A. Neil


Book ID
112340691
Publisher
Springer-Verlag
Year
1984
Tongue
English
Weight
613 KB
Volume
328
Category
Article
ISSN
0028-1298

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The presence of pairs of basic amino acids within the orphanin FQ/Nociceptin (OFQ/N) sequence has raised the possibility that truncated versions of the peptide might be physiologically important. OFQ/N(1-11) is pharmacologically active in mice, despite its poor affinity in binding assays (K i ΟΎ 250