✦ LIBER ✦
Aerobic oxidation of 8,11,13-abietatrienes catalyzed by N-hydroxyphthalimide combined with 2,2′-azobis(4-methoxy-2,4-dimethylvaleronitrile) and its application to synthesis of naturally occurring diterpenes
✍ Scribed by Yoh-ichi Matsushita; Kazuhiro Sugamoto; Yoshihisa Iwakiri; Satoru Yoshida; Takehito Chaen; Takanao Matsui
- Book ID
- 104097878
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- French
- Weight
- 521 KB
- Volume
- 51
- Category
- Article
- ISSN
- 0040-4039
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✦ Synopsis
Methyl 8,11,13-abietatriene-18-oate (1b) and 7-oxo-8,11,13-abietatrienes 10 and 15 were converted into 15-hydroperoxy-7-oxo-8,11,13-abietatrienes 13 and 16 by aerobic oxidation catalyzed by N-hydroxyphthalimide (NHPI) combined with 2,2 0 -azobis(4-methoxy-2,4-dimethylvaleronitrile) (V-70) at room temperature, and several abietane and podocarpane terpenes were synthesized from 13 and 16.