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Aerobic exercise and muscle metabolism in patients with mitochondrial myopathy

✍ Scribed by Michael I. Trenell; Carolyn M. Sue; Graham J. Kemp; Toos Sachinwalla; Campbell H. Thompson

Publisher: John Wiley and Sons
Year: 2006
Tongue: English
Weight: 132 KB
Volume: 33
Category: Article
ISSN: 0148-639X
DOI: 10.1002/mus.20484

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Analysis of mitochondrial DNA (mtDNA) in muscle and blood from 72 patients with mitochondrial myopathy showed that 30 had major deletions of a variable proportion of muscle mtDNA. All of these 30 patients presented with progressive external ophthalmoplegia and limb weakness, and 8 had the additional