Adverse effects of dopamine potentiation by long-term treatment with selegiline
✍ Scribed by Susan Hollán; László Vécsei; Kálmán Magyar
- Publisher
- John Wiley and Sons
- Year
- 2003
- Tongue
- English
- Weight
- 53 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0885-3185
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
A patient with triosephosphate isomerase (TPI) deficiency exhibited worsening of abnormal involuntary movements of the dystonic type and developed psychiatric symptoms while on selegiline. When selegiline was stopped after 9 years of treatment, abnormal involuntary movements improved to pretreatment level and psychiatric behaviour returned to normal. Monoamine oxidase‐B platelet activity was low in this patient. © 2003 Movement Disorder Society
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