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Adverse effects of anticholinergic activity on cognitive functions in Alzheimer's disease

โœ Scribed by Kimiko KONISHI; Koji HORI; Hiroyuki UCHIDA; Koichiro WATANABE; Itaru TOMINAGA; Masaki KIMURA; Makoto HOSOYAMADA; Toshiaki SHIBASAKI; Akira KATAOKA; Mitsugu HACHISU


Book ID
109059083
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
242 KB
Volume
10
Category
Article
ISSN
1346-3500

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The contribution of cholinergic dysfunction to the non-mnestic cognitive impairments associated with senile dementia of the Alzheimer type (SDAT) was investigated. Scopolamine (0 . 5 mg) was administered intravenously to 12 healthy individuals, and their performance on selected subtests of the Wechs