Adverse effect of verapamil in a patient with the lambert-eaton syndrome
โ Scribed by Dr. David A. Krendel; Linton C. Hopkins
- Publisher
- John Wiley and Sons
- Year
- 1986
- Tongue
- English
- Weight
- 354 KB
- Volume
- 9
- Category
- Article
- ISSN
- 0148-639X
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## Abstract Intravenous immunoglobulin (IVIg) treatment improves muscle strength in LambertโEaton myasthenic syndrome (LEMS), but its specific mode of action is unknown. We have delineated its mode of action on neuromuscular blocking properties of LEMS IgG. The effect of sera and purified IgG from
## FIGURE 1. Repetitive nerve stimulation of right ulnar nerve with recording on adductor digiti quiniti muscle. Top: 3 Hz, 27% decrement of the fourth response of the compound muscle action potential. Bottom: 20 Hz, 50% decrement of the fourth response followed by increment and marked decrement.