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Advantages and limitations of mouse models to deplete dendritic cells

✍ Scribed by van Blijswijk, Janneke; Schraml, Barbara U.; Sousa, Caetano Reis e

Book ID: 118758126
Publisher: John Wiley and Sons
Year: 2013
Tongue: English
Weight: 538 KB
Volume: 43
Category: Article
ISSN: 0014-2980
DOI: 10.1002/eji.201243022

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## Abstract IL‐33 is becoming a central molecule in allergic asthma that addresses various cascades of innate and adaptive immune responses that lead to inflammation in the lung. Its effects are exerted via its heterodimeric receptor that consists of ST2 and the ubiquitously expressed IL‐1 receptor