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Advantages and challenges of mass spectrometry assays for steroid hormones

✍ Scribed by Frank Z. Stanczyk; Nigel J. Clarke


Book ID
116698564
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
134 KB
Volume
121
Category
Article
ISSN
0960-0760

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Liquid chromatography–mass spectrometry
✍ Trevor M. Penning; Seon-Hwa Lee; Yi Jin; Alejandro Gutierrez; Ian A. Blair πŸ“‚ Article πŸ“… 2010 πŸ› Elsevier Science 🌐 English βš– 406 KB

Advances in liquid chromatography-mass spectrometry (LC-MS) can be used to measure steroid hormone metabolites in vitro and in vivo. We find that LC-electrospray ionization (ESI)-MS using a LCQ ion trap mass spectrometer in the negative ion mode can be used to monitor the product profile that result