## Background: Bone cancer pain is very common, and patients with this type of pain may be difficult to treat. development of an experimental model for studying this condition is critical to advancing an understanding of the mechanisms that cause pain in patients with malignant disease. ## Methods
Advances in understanding bone cancer pain
β Scribed by M.J. Goblirsch; P. Zwolak; D.R. Clohisy
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 285 KB
- Volume
- 96
- Category
- Article
- ISSN
- 0730-2312
No coin nor oath required. For personal study only.
β¦ Synopsis
Abstract
Experimental animal models of bone cancer pain have emerged and findings have provided a unique glimpse into unraveling the mechanism that drives this debilitating condition. Key contributors to the generation and maintenance of bone cancer pain are tumorβinduced osteolysis, tumor itself, and production of nociceptive mediators in the boneβtumor microenvironment. J. Cell. Biochem. Β© 2005 WileyβLiss, Inc.
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