## Abstract We used arrayβbased comparative genomic hybridization (aCGH) to measure genomic copy number alterations (CNAs) in 42 neuroblastoma cell lines with known 1p36.3, 2p24 (__MYCN__), 11q23, and 17q23 allelic status. All cell lines showed CNAs, with an average of 22.0% of the genome of each s
β¦ LIBER β¦
Advances in the understanding of constitutional and somatic genomic alterations in neuroblastoma
β Scribed by Rebecca J. Deyell; Edward F. Attiyeh
- Book ID
- 116332578
- Publisher
- Elsevier
- Year
- 2011
- Tongue
- English
- Weight
- 438 KB
- Volume
- 204
- Category
- Article
- ISSN
- 2210-7762
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## Abstract We performed DNA microarrayβbased comparative genomic hybridization to identify somatic alterations specific to melanoma genome in 60 human cell lines from metastasized melanoma and from 44 corresponding peripheral blood mononuclear cells. Our data showed gross but nonrandom somatic cha