𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Advances in the staging and treatment of ovarian cancer

✍ Scribed by Richard I. Fisher; Robert C. Young

Publisher
John Wiley and Sons
Year
1977
Tongue
English
Weight
563 KB
Volume
39
Category
Article
ISSN
0008-543X

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✦ Synopsis

The age adjusted death rate for ovarian cancer has remained unchanged for the past 20 years. Recent data obtained by staging ovarian cancer patients with lymphangiography and peritoneoscopy demonstrated that many patients with apparently localized disease actually have occult dissemination within the abdomen. These new staging techniques plus the determination of the histologic grade of anaplasia may permit a more precise determination of a patient's prognosis and therefore better design of therapeutic stategy. Radiotherapeutic techniques are being adapted to attempt to treat some areas of occult disease. Numerous single chemotherapeutic agents are capable of producing objective tumor responses. Preliminary data suggest that combination chemotherapy can increase the objective response rate above that seen with single agents. Longer follow-up is necessary to determine whether combination chemotherapy can prolong survival.

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✍ Carolyn D. Runowicz; Abbie L Fields; Gary L. Goldberg πŸ“‚ Article πŸ“… 1995 πŸ› John Wiley and Sons 🌐 English βš– 599 KB

Advanced stage ovarian cancer is the most lethal gynecologic cancer. Despite initial response rates of 60-80'/0 with platinum-based chemotherapy, more than 75% of women with this malignancy die of complications associated with this disease. There is a pressing need to find new chemotherapeutic agent