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Advances in the genetics and epigenetics of gene regulation and human disease

✍ Scribed by Kristine Kleivi

Book ID: 120702435
Publisher: BioMed Central
Year: 2006
Tongue: English
Weight: 57 KB
Volume: 7
Category: Article
ISSN: 1465-6906
DOI: 10.1186/gb-2006-7-8-325

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## Abstract Lipoprotein lipase (__LPL__) is in chromosome 8p22, site of one of the most common somatic deletions in prostate tumors. Additionally, a CpG island (CGI) was identified in the __LPL__ promoter region. To test the hypothesis that __LPL__ is a tumor suppressor gene, which is inactivated b