Advances in Research and Applications

✍ Scribed by Gerald Litwack

• Publisher: Elsevier, Academic Press
• Year: 2000
• Tongue: English
• Leaves: 503
• Series: Vitamins & Hormones 58
• Edition: 1
• Category: Library

✦ Synopsis

Under the capable and qualified editorial leadership of Dr. Gerald Litwack, Vitamins and Hormones continues to publish cutting-edge reviews of interest to endocrinologists, biochemists, nutritionists, pharmacologists, cell biologists, and molecular biologists. First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. In the early days of the Serial, the subjects of vitamins and hormones were quite distinct. Now, new discoveries have proved that several of the vitamins function as hormones and many of the substances inferred by the title of the serial function in signal transduction processes. Accordingly, the Editor-in-Chief has expanded the scope of the serial to reflect this newer understanding of function-structure relationships in cellular communication. The Editorial Board now reflects expertise in the field of hormone action, vitamin action, X-ray crystal structure, physiology, and enzyme mechanisms.

✦ Table of Contents

Content:
Editorial Board
Page iv

Preface
Page xiii
Gerald Litwack

Protein folding and deficiencies caused by dominant-negative mutants of hormones Review Article
Pages 1-26
Priscilla S. Dannies

Structural aspects of the G-protein receptor, rhodopsin Review Article
Pages 27-51
Arlene D. Albert, Philip L. Yeagle

Molecular modeling of mammalian cytochromes P450: Application of study enzyme function Review Article
Pages 53-87
Grazyna D. Szklarz, Sandra E. Graham, Mark D. Paulsen

Prostaglandin D synthase: Structure and function Review Article
Pages 89-120
Yoshihiro Urade, Osamu Hayaishi

Steroid dehydrogenase structures, mechanism of action, and disease Review Article
Pages 121-148
William L. Duax, Debashis Ghosh, Vladimir Pletnev

Structure-based inhibitor design Review Article
Pages 149-169
Sydney P. Craig III, Ann E. Eakin

Protein folding using contact maps Review Article
Pages 171-212
Michele Vendruscolo, Eytan Domany

HIV protease: Enzyme function and drug resistance Review Article
Pages 213-256
Sergei Gulnik, John W. Erickson, Dong Xie

Ultrastructure of cells undergoing apoptosis Review Article
Pages 257-266
Kenji Kimura, Hironobu Sasano, Tooru Shimosegawa, Shizue Mochizuki, Hiroshi Nagura, Takayoshi Toyota

Role of cytoskeleton in apoptosis Review Article
Pages 267-297
R. Atencia, A. Asumendi, M. García-Sanz

Dietary antioxidants and cardiovascular disease Review Article
Pages 299-320
J. Michael Gaziano

Melatonin receptors and ligands Review Article
Pages 321-354
Paula A. Witt-Enderby, Pui-Kai Li

Vitamin K-dependent proteins Review Article
Pages 355-389
Gary L. Nelsestuen, Amit M. Shah, Stephen B. Harvey

Steroid/nuclear receptor coactivators Review Article
Pages 391-448
J.Don Chen

Thyroid hormone receptor, v-erbA, and chromatin Review Article
Pages 449-492
Alan P. Wolffe, Trevor N. Collingwood, Qiao Li, Janet Yee, Fyodor Urnov, Yun-Bo Shi

Index
Pages 493-505