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Advances in phosphopeptide enrichment techniques for phosphoproteomics

✍ Scribed by Beltran, Luisa; Cutillas, Pedro R.

Book ID
120156225
Publisher
Springer
Year
2012
Tongue
English
Weight
652 KB
Volume
43
Category
Article
ISSN
0939-4451

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## Abstract Mass spectrometry is the tool of choice to investigate protein phosphorylation, which plays a vital role in cell regulation and diseases such as cancer. However, low abundances of phosphopeptides and low degrees of phosphorylation typically necessitate isolation and concentration of pho