Advances in Intravital Microscopy: From Basic to Clinical Research

✍ Scribed by Roberto Weigert (eds.)

• Publisher: Springer Netherlands
• Year: 2014
• Tongue: English
• Leaves: 425
• Edition: 1
• Category: Library

✦ Synopsis

This is the first book entirely dedicated to Intravital Microscopy. It provides the reader with a broad overview of the main applications of Intravital Microscopy in various areas of the biomedical field. The book contains accurate descriptions of the state of the art methodologies used to image various organs at different level of resolution, ranging from whole tissue down to sub-cellular structures. Moreover, it is an extremely valuable guide to scientists that want to adopt this powerful technique and do not have experience with animal models and microscopy.

✦ Table of Contents

Front Matter....Pages i-viii
Intravital Two-Photon Excitation Microscopy in Neuroscience: General Concepts and Applications....Pages 1-23
Two-Photon Imaging of Cerebral Vasodynamics in Awake Mice During Health and Disease....Pages 25-43
In Vivo Imaging in Neurodegenerative Diseases....Pages 45-80
Intravital Imaging of the Immune System....Pages 81-103
Cancer in the Spotlight: Using Intravital Imaging in Cancer Research....Pages 105-123
Haemodynamics and Oxygenation of the Tumour Microcirculation....Pages 125-141
In Vivo Imaging of Bone Marrow Stem Cells....Pages 143-162
Live Imaging of Subcellular Structures and Cellular Processes in Mouse Intraperitoneal Organs....Pages 163-185
Intravital Imaging of the Lactating Mammary Gland in Transgenic Mice Expressing Fluorescent Proteins....Pages 187-204
Fluorescent Dextrans in Intravital Multi-Photon Microscopy....Pages 205-219
Intravital Microscopy of the Lung....Pages 221-232
Intravital Microscopy for Molecular Imaging in Cancer Research....Pages 233-262
Imaging Drug Distribution and Effects at the Single Cell Level In Vivo....Pages 263-280
Nonlinear Endomicroscopy Imaging Technology for Translational Applications....Pages 281-303
Intravital Multiphoton Endoscopy....Pages 305-370
Fluorescence Lifetime Imaging for Diagnostic and Therapeutic Intravital Microscopy....Pages 371-418
Back Matter....Pages 419-424

✦ Subjects

Biomedicine general; Life Sciences, general; Biological Microscopy; Animal Physiology