To assess the prevalence of antibodies to hepatitis A virus (anti-HAV) in future travellers, all visitors to the Zurich University Vaccination Center in July/August 1990 were invited to participate in a cross-sectional study. A total of 1126 future travellers were recruited to have a blood sample dr
Advances in hepatitis A prevention in travellers
β Scribed by Professor R. Steffen; D. Gyurech
- Publisher
- John Wiley and Sons
- Year
- 1994
- Tongue
- English
- Weight
- 316 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0146-6615
No coin nor oath required. For personal study only.
β¦ Synopsis
Abstract
The introduction of an active vaccine against hepatitis A, the most frequent of the vaccinepreventable infections in travellers, is an important contribution to travellers' health. Although theoretically the risk of exposure may be minimised by taking hygienic precautions, most travellers in practice remain at considerable risk. As compared to immunoglobulin, vaccine has the advantages of better and longβlasting protection. A doubleβstrength vaccine has been introduced (HAVRIX(tm), 1440 enzymeβlinked immunosorbent [ELISA] units [EL. U]) and a single injection will protect from day 14 for 1 year. No significant adverse events have been reported. Questions that remain unanswered are whether travellers leaving before day 14 should receive immune globulin plus vaccine and whether very young travellers should all be immunised. Β© 1994 WileyβLiss, Inc.
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