Advances in hepatic resection and results for hepatocellular carcinoma

✍ Scribed by Toshiaki Nonami; Akio Harada; Tsuyoshi Kurokawa; Akimasa Nakao; Hiroshi Takagi

• Publisher: John Wiley and Sons
• Year: 1996
• Tongue: English
• Weight: 590 KB
• Volume: 12
• Category: Article
• ISSN: 8756-0437
• DOI: 10.1002/(sici)1098-2388(199605/06)12:3<183::aid-ssu7>3.0.co;2-3

✦ Synopsis

The mortality and morbidity of hepatic resection for hepatocellular carcinoma (HCC) have decreased in recent years because of the various advances in hepatic resection. Various improvements are evident in dissecting apparatus, liver hepatic inflow clamp, cold hepatic perfusion technique, intraoperative ultrasonography, accurate assessment of hepatic function, autologous blood transfusion, and so on. Fiveyear survival after hepatic resection for HCC was reported at 26-59% in Eastern as well as Western series. The prognostic factors were portal invasion, multiplicity, serum a-fetoprotein level, tumor size, associated cirrhosis, age, alcohol abuse, histologic classification, DNA ploidy, and surgical margin. Segmental or lobar hepatic resection brought about better survival, especially in stage I and I1 patients. Effective adjuvant therapy should improve the diagnosis.