[Advances in Genetics] Non-Viral Vectors for Gene Therapy, Second Edition: Part 2 Volume 54 || In Vivo Application of RNA Interference: From Functional Genomics to Therapeutics

✍ Scribed by Lu, Patrick Y.

• Book ID: 120902810
• Publisher: Elsevier
• Year: 2005
• Tongue: English
• Weight: 360 KB
• Edition: 2
• Category: Article
• ISBN: 0120176548
• DOI: 10.1016/S0065-2660(05)54006-9

✦ Synopsis

The field of non-viral vector research has rapidly progressed since the publication of the first edition. This new edition is expanded to two separate volumes that contain in-depth discussions of different non-viral approaches, including cationic liposomes and polymers, naked DNA and various physical methods of delivery, as well as a comprehensive coverage of the molecular biological designs of the plasmid DNA for reduced toxicity, prolonged expression and tissue or disease specific genes. New developments such as the toxicity of the non-viral vectors and recent advances in nucleic acid therapeutics are fully covered in these volumes.