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[Advances in Experimental Medicine and Biology] Current Topics in Complement Volume 586 || Liver Regeneration: A Link to Inflammation through Complement

✍ Scribed by Lambris, John D.


Book ID
121510334
Publisher
Springer US
Year
2006
Tongue
English
Weight
218 KB
Edition
2006
Category
Article
ISBN
0387322310

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✦ Synopsis


Complement Has Long Been Regarded As A Pivotal Effector Arm Of The Innate Im-mune Response, Eliciting Important Immunoregulatory Functions In The Context Of Inflammation And Also Serving As A Vital Link Between The Innate And Adaptive Immune Response. In The Post-genomic Era, Our Knowledge Of The Innate Immune System Is Enriched By Findings That Point To Novel Functions That Do Not Strictly Correlate With Immunological Defense And Surveillance, Immune Modulation Or Inflammation. Several Studies Indicate That Complement Proteins Exert Functions That Are Either More Complex Than Previously Thought, Or Go Well Beyond The Innate Immune Character Of The System. The Advent Of High-throughput Platforms For Genome And Proteome-wide Profiling, Together With The Enormous Amount Of Raw Genetic Information That Has Accumulated In The Databases, Have Stirred New Expectations In Biomedical Research. They Have Led Complementologists To Revisit Established Biological Systems, Such As The Com. Cross-disciplinary Research Stirs New Challenges Into The Study Of The Structure, Function, And Systems Biology Of Complement / Dimitrios Mastellos And John D. Lambris -- Liver Regeneration: A Link To Inflammation Through Complement / Robert A. Deangelis, Maciej M. Markeiwski, And John D. Lambris -- The Role Of Third Complement Component (c3) In Homing Of Hematopoietic Stem/progenitor Cells Into Bone Marrow / Ryan Reca ... [et Al.] -- Complement System And The Eye / Purushottam Jha ... [et Al.] -- To Regeneration-- With Complement / Panagiotis A. Tsonis, John D. Lambris, And Katia Del Rio-tsonis. C5b-9 Complement Complex In Autoimmune Demyelination: Dual Role In Neuroinflammation And Neuroprotection / Horea Rus, Cornelia Cudrici, And Florin Niculescu -- The Double-edgd Flower: Roles Of Complement Protein C1q In Neurodegenerative Diseases / Andrea J. Tenner And Maria I. Fonseca -- The Role Of The Complement System In The Pathogenesis Of Experimental Autoimmune Encephalomyelitis And Multiple Sclerosis / NΓ³ra TerΓ©nyi, JΓ³zef Prechl, And Anna Erdei -- The Complement System: A Potential Target For Stroke Therapy / J. Mocco ... [et Al.]. Inactivation Of Complement By Recombinant Human C3 Derivatives / Edzard Spillner, Johanna KΓΆlln, And Reinhard Bredehorst -- Complement Analysis In Clinic And Research / Tom E. Mollnes And Michael Kirschfink -- Cell-bound Complement Activation Products (cb-caps) As A Source Of Lupus Biomarkers / Sarah J. Calano ... [et Al.]. Observations On Complement Activity In The Two-stage Inflammatory/hemostatic Response In The Baboon And Human Models Of E. Coli Sepsis And Endotoxemia / Fletcher B. Taylor, Jr., Eric Hack, And Florea Lupu -- Complement Activation During Sepsis In Humans / Heike Schreiber ... [et Al.] -- Three Distinct Profiles Of Serum Complement C4 Proteins In Pediatric Systemic Lupus Erythematosus (sle) Patients: Tight Associations Of Complement C4 And C3 Protein Levels In Sle But Not In Healthy Subjects / Yee-ling Wu ... [et Al.] -- A Minimum Cr2 Binding Domain Of C3d Enhances Immunity Following Vaccination / Joseph F. Bower And Ted M. Ross. Self, Non-self And Danger: A Complementary View / JΓΆrg Kohl -- Gclqr/p33 Serves As A Molecular Bridge Between The Complement And Contact Activation Systems And Is An Important Catalyst In Inflammation / Berhane Ghebrehiwet ... [et Al.] -- Possible Immunoprotective And Angiogenesis-promoting Roles For Malignant Cell-derived Prostasomes: A New Paradigm For Prostatic Cancer ? / Kristina Nilsson Ekdahl ... [et Al.] -- Diversified Components Of The Bony Fish Complement System: More Genes For Robuster Innate Defense? / Miki Nakao ... [et Al.]. Structure And Function Of Ficolins / Yuichi Endo, Yu Liu, And Teizo Fujita -- Role Of Mannose-binding Lectin (mbl2) Genotyping In Predicting The Risk Of Recurrent Otitis Media (rom) / Lieve Nuytinck ... [et Al.] -- Conformational Complexity Of Complement Component C3 / Bert J.c. Janssen And Piet Gros -- Disease-associated Sequence Variations In Factor H: A Stuctural Biology Approach / Andrew P. Herbert ... [et Al.] -- Transdermal Pharmacology Of Small Molecule Cyclic C5a Antagonists / Lavinia M. Proctor ... [et Al.]. Edited By John D. Lambris. Topics Discussed At Third Aegean Conferences Workshop On Complement Associated Diseases, Animal Models, And Therapeutics, June 5-10, 2005--pref. Includes Bibliographical References And Index.


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