The most tangible advances in DNA diagnostics during the past year have been in enhancing existing techniques to simplify their use and improve throughput. This has led to simplified genotyping methods using homogeneous analysis coupled with spectral data output. Miniaturisation and increased throug
Advances in DNA diagnostics
โ Scribed by Joel H Graber; Maryanne J O'Donnell; Cassandra L Smith; Charles R Cantor
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- English
- Weight
- 497 KB
- Volume
- 9
- Category
- Article
- ISSN
- 0958-1669
No coin nor oath required. For personal study only.
โฆ Synopsis
The key advances in DNA diagnostics during the past year are techniques which will lead to advanced throughput without sacrificing sensitivity: miniaturization of samples to reduce material cost and preparation time, and parallelization through use of measurement arrays. The most promising gains have come in the areas of DNA arrays and mass spectrometry, where differential sequencing measurements are now possible.
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