Advances in cytomegalovirus-preventive strategies in solid organ transplantation: defending pre-emptive therapy
✍ Scribed by Reischig, Tomáš
- Book ID
- 111687264
- Publisher
- Expert Reviews
- Year
- 2012
- Tongue
- English
- Weight
- 341 KB
- Volume
- 10
- Category
- Article
- ISSN
- 1478-7210
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## Abstract Cytomegalovirus is a significant cause of morbidity and mortality in transplantation. Controversy exists concerning whether prophylactic or pre‐emptive therapy is the optimal strategy for preventing CMV disease. In addition, CMV impacts the transplanted graft, transplant recipient and t
## Abstract Pre‐emptive therapy (PET) initiated on the basis of HCMV positivity in the blood using sensitive methods such as PCR, nucleic acid sequence based amplification or antigenaemia offers several advantages for the management of HCMV infection. These include the ability to target antiviral d